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2000 CE – Present
1960 CE – 2000 CE
1940 CE – 1960 CE
1900 CE – 1940 CE
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1400 CE – 1800 CE
400 CE – 1400 CE
1 CE – 400 CE
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Evidence relevant to Synergy
Benefits of intimacy
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Costs of disharmony
Costs of isolation
Shifts after sex
Too much?
Post-climax cravings
Pair bonding
Human pair bonding
Honeymoon neurochemistry
Coolidge effect (habituation)
Competing stimuli
Neurobiology of pair bonding
Neurochemical cycle after climax
Dopamine
Dopamine and sexual behaviour
Dopamine and mood, cognition, cravings and perception
Oxytocin and climax
Arousal (non-dopamine)
Post-climax effects
Dopamine
Androgen receptors and serum testosterone
Opioids
Endocannabinoids
Serotonin
Prolactin
Glutamate
Other physiological shifts
Sex and drug use overlap
Sexual learning and brain plasticity
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