Bonde nekushandisa zvinodhaka zvinogona kupindana sei? Zvepabonde, kupindwa muropa nemaitiro akapindwa muropa nezvinodhaka zvinogovana nezvinowanzoitika. Dzinoguma nekuchinja kwakadai kweuropi. Uku kuwanda kunoonekwa mukutsvaga. Pazasi iwe unowana sampling yebasa munzvimbo ino.

Kupindirana kunobatsira kutsanangura kuti bonde rinogona sei kukanganisa zvakanyanya maonero nekutanga. Zvepabonde uye kushandisa zvinodhaka shanduko dzinoitika nekusaziva. Nekudaro, isu kazhinji hatisi kucherechedza yavo (dzimwe nguva yakadzika) mhedzisiro pamaonero edu, zvakakosha uye sarudzo.

vanhu

Makomborero echisikigo, Neuroplasticity, uye Zvisingabatsiri Zvinodhaka

Anomanikidzwa Kuita Bonde muvanhu uye Preclinical Models

Kufananidzira kwehupombwe hwekuita zvepabonde kwevanhu: Kuvandudzwa kwezvino munguva pfupi uye Kwemangwana Mazano (2017)

Brain Activation panguva yekubuda kwemurume murume (2003)

Animals

Amphetamine mubairo mune monogamous prairie vole

Kukanganisika kweruzivo rwemubhadharo wezvemagariro pane maitiro ane maitiro kune zvinodhaka zvekushungurudza: Ongororo yeiyo yakagovaniswa uye yakatsaukana neural plasticity maitiro emubhadharo wepabonde uye zvinodhaka zvekushungurudza

Ventral Tegmental Area Dopamine Cell activation panguva Yechirume Bonde Kuzvibata Kunotonga Neuroplasticity uye d-Amphetamine Cross-Sensitization ichitevera Kuita Bonde

Maladaptive Kuita Bonde Kuitevedzera Zvakafanana Methamphetamine uye Kuita Zvepabonde mu Varume Mapundu Kunobatanidzwa neAlpent Neural Activity muFontont Cortex.

Cell-Type chaiyo inowedzera mune yechikadzi hamster nucleus inounganidza spine density inotevera mukadzi ruzivo rwepabonde

Shanduko mukutaura kwejini mukati meiyo nucleus inounganidza uye striatum inotevera chiitiko chebonde

Kuwanikwa pachena kwe methamphetamine nehunhu hwepabonde kunowedzera mubairo unotevera weinodhaka uye kukonzera maitiro ekumanikidza ezvepabonde mumakonzo ehurume

Nzira dzeshungu dzebonde

Endo native opioid-induced neuroplasticity ye dopaminergic neurons munharaunda ye ventral tegmental nzvimbo inofurira yemasikirwo uye opiate mubairo.

Methamphetamine inobata pane zvishoma zvehutachiona hutsika hwehupombwe mumakumbo evarume

Natural mubayiro ruzivo zvinoshandura AMPA uye NMDA receptor kugovera uye basa muiyo nucleus accumbens

Makomborero echisikigo, Neuroplasticity, uye Zvisingabatsiri Zvinodhaka

Ruzivo rwepabonde rinoshandura D1 receptor -ediya cyclic AMP kugadzirwa muiyo nucleus inosunganidza yevakadzi veSyria hamsters

Ruzivo rwepabonde mumakonzo echikadzi: maseru maitiro uye maitiro anoshanda

Neuroplasticity muMesolimbic System Inotakurwa neakasikwa Mubairo uye Inotevera Mubairo Kuzviramba

Chiitiko chebonde chinonzwa mating-anoenderana nehunyoro anounganidza dopamine mhinduro dzevakadzi veSyria hamsters

Mubairo wepabonde mune makonzo echirume: Mhedzisiro yekusangana pabonde pane yakasarudzika nzvimbo zvido zvinosangana neyekura uye kupinda mukati

Kudzoka kubva pakuneta kwepabonde-kunokonzerwa kukanganisa kusagadzikana uye kushandiswa kwemishonga inokonzerwa nemishonga inotevera nguva imwechete: maitiro maviri ehumwechete?

Ubongo Hwakagadziriswa panguva yeHuman Male Ejaculation

Maitiro anofungidzirwa akakonzerwa nepabonde uye zvinodhaka: kuenzaniswa kwezvigadzirwa zve neural

DeltaFosB, c-Fos, uye DeltaJunD

Aya mapepa anoongorora zvakanyatsonaka, hunyanzvi hwese hwekuti bonde nekushandisa zvinodhaka zvinogona kupindirana

Kufuridzirwa kweAFosB muNucleus Accumbens kuMutengo Wemagariro Akabatana Nehutano

DeltaFosB Overexpression Mune Iyo Nucleus Inowedzera Inovhiringidza Kurara Kwebonde Mu Mukadzi Syrian Hamsters.

DeltaFosB muNucleus Accumbens inonyanya kukosha yekuvandudza migumisiro yepabonde repabonde

Delta JunD overexpression muiyo nyukadzira bokosi inodzivirira mubayiro wepabonde muvakadzi veSyria hamsters

DeltaFosB: yakaramba ichishandiswa mumashonga ekudhakwa

Mitemo yemasikirwo emitemo uye yemishonga Mutemo pa Common Neural Plasticity Maitiro neAFosB seMurevereri Mukuru

Kuita zvepabonde Kuchengetedza c-Fos muNucleus Accumbens uye Amphetamine-Stimulated Locomotor Basa Inogamuchirwa neZviitiko Zvepabonde Zvakaitika Kare Mukadzi weSyria Hamsters