Iko kufambidzana kungangoitika kweyeohimbine neiyo dopaminergic system mukumiririra kwekuita zvepabonde kutaura mune zvepabonde zvakaneta makonzo echirume akaongororwa. Maitiro ekukuvadza kweaya panguva imwechete jekiseni yohimbine (500 microg / kg) pamwe apomorphine (50 microg / kg) uye izvo zvekurapa kwakabatana kwe haloperidol (125 microg), nonspecific dopamine receptor antagonist, ine mushonga unoshanda weyohimbine (2000 microg / kg) pamakonzo akasangana pabonde akaongororwa. Nhoroondo inoratidza kuti yohimbine uye apomorphine, pa se, dhi-yakavimbika inodzoreredza kupera simba pabonde nekuwedzera iyo muzana yezvepabonde yakagadziriswa makonzo kutevedzera uye kutangazve kutevedzera mushure mekupa. In injion ye haloperidol panguva imwe chete kune inoshanda mushonga yohimbine, yakavharidzira kugona kweyekupedzisira kudzosera zvepabonde satiation. Kurapa kwakabatanidzwa pamwe nekunyorwa pasi madhidhi eapomorphine uye yohimbine synergised kudzoreredza hutachiona hwehutachiona hunhu hwekupera simba pabonde. Dhata inoratidza kuti iyo dopaminergic system inogona kunge iri yekupedzisira nzira yeiyoohimbine-inosimudzira tsika yekuita zvepabonde mumapati akagutsikana. Basa rinogoneka rekusimudzira pabonde mune chinhu chekupera simba pabonde rinokurukurwa.