Previous studies have found that women report more orgasm and sexual satisfaction from sex in committed relationships than from casual sex. We examined whether sociosexual orientation was associated with these differences, and explored the links between sociosexuality and sexual outcomes in these two sexual relationship contexts. Sexually active women (n = 1,084) completed an online survey measuring sociosexual orientation, orgasmic function, and sexual satisfaction. Participants reported sexual outcomes (orgasmic function and sexual satisfaction) with respect to their sexual activity over the past 12 months in a casual context (if applicable), and separately in a committed context (if applicable). Among women who had both casual and committed sex in the past year, orgasmic function and sexual satisfaction differed between these two relationship contexts only for more sexually restricted women (lower sociosexuality). In the full sample, higher sociosexuality was associated with higher orgasmic function in casual sex and with lower sexual satisfaction in committed sex. These findings underscore the importance of examining interactions between individual differences and contextual factors when studying women’s sexual outcomes.