Glutamate is the most abundant neurotransmitter in the brain. It is involved in virtually every major brain function. Glutamate plays a prominent role in neuroplasticity—the brain’s ability to strengthen or weaken signaling between neurons over time in order to shape learning and memory.

Animal

Astrocytes in the medial preoptic area modulate ejaculation latency in an experience-dependent fashion.

Glutamatergic transmission is involved in the long lasting sexual inhibition of sexually exhausted male rats.