28 Apr 1978: Vol. 200, Issue 4340, pp. 451-453 DOI: 10.1126/science.417398

RP Michael, D Zumpe


Ejaculations decreased and mount latencies increased when intact males were paired regularly over a 3.5-year period (3180 tests) with ovariectomized females made constantly receptive by daily injections of estradiol. The deterioration in potency was abruptly and completely reversed by substituting a group of new but similarly treated females for the original ones.